Dissolve the lyophilized (dry) component in the liquid component before using the vaccine. Inject into the thigh area or subcutaneously at 8-10 weeks, repeat after 21-28 days. Puppies are revaccinated at the age of 10-12 months. Adult dogs are vaccinated once a year with a dose of 2 ml. Small dogs are vaccinated with a dose of 1 ml.